Meet Cathy Tie: The Bride of “China’s Frankenstein”

Key Takeaways

  • He’s social media posts have become more provocative, raising curiosity among followers.
  • He recently married Tie in a sudden ceremony, sparking speculation about their relationship.
  • Tie is a notable entrepreneur who gained early recognition through the Thiel Fellowship.

In April, He’s social media presence underwent a noticeable change as his posts became increasingly provocative. These updates featured improved English and a distinct tone that resonated with online culture. On April 15, He quipped, “Stop asking for cat girls. I’m trying to cure disease.” This was followed two days later by another striking statement: “I literally went to prison for this shit.” This dramatic shift in content coincided with his budding romance with Tie, a factor that has intrigued and puzzled followers.

Beautifully illustrating their whirlwind romance, Tie revealed that she visited China three times this year, including a three-week stay in April during which she and He married. She presented He with a unique silver wedding ring crafted to resemble intertwined DNA strands. This unexpected union, alongside He’s erratic behavior on social media, has led followers to speculate whether they are witnessing a love story, entrepreneurial venture, or a form of performance art—perhaps a blend of all three.

A wedding photo shared by Tie on the Chinese platform Rednote captured the couple at a banquet hall table, accompanied by a modest gathering of guests. Among those identified at the event were Cai Xilei, He’s criminal attorney; Liu Haiyan, an investor and former associate of He; and Darren Zhu, an artist working on a speculative documentary that aims to blur the lines between fiction and reality surrounding the biophysicist’s life.

During a phone interview, Tie refrained from confirming whether her marriage to He was legally binding. She revealed she previously celebrated a wedding in California in July 2024, which ended shortly afterward. Despite her previous relationship, Tie asserted that her bond with He is sincere, stating, “I wouldn’t marry him if I wasn’t in love with him.”

Years prior to her relationship with He, Tie was gaining significant attention in her own right. She became a Thiel fellow at just 18, receiving a $100,000 grant to drop out of the University of Toronto and launch her gene-testing startup, Ranomics. Her accomplishments soon led her to be featured on Forbes’ “30 Under 30” list in 2018, and she appeared on CNN as an emerging venture capitalist that same year. In 2020, she founded her second company, Locke Bio, focused on telemedicine.

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